About the lab

 

Our laboratory studies the tissue-level mechanisms responsible for musculoskeletal integrity in health and disease. We utilize numerous in vivo model systems to understand how disease and pharmaceutical intervention influence bone structure, cellular activity, tissue-level properties (such as mineralization, microdamage, collagen, hydration), and biomechanical properties.

 

We study diseases/conditions such as osteoporosis, diabetes, chronic kidney disease, disuse,and aging using techniques such as imaging (CT, DXA, X-ray), histology (static and dynamic histomorphometry, microdamage), and mechanical testing (bending, compression, reference point indentation).

 

Our laboratory is funded by the National Institutes of Health, NASA/NSBRI, IU School of Medicine, and industry.